Immunological and Seriological Profile of Arthritis

Arthritis is one of the common diseases. in this present study twenty patients with symptoms of arthritis were included is as control another twenty patients without arthritis are included. The serum samples of these patients were collected and left for RF(or) RA which detects the immunoglobulin of the class IgM, IgA and IgE and careful prognostic marker of RA ie IgM is detected. Different reagents like RHELAX RF reagent, positive control, and negative control are used. Mean while interpretation of rest results were observed. An enhanced immuno turbiclimetric test i.e CRP test was conducted (c-reactive protein Turbilaten), which represents a useful laboratory test for diction of acute infection as well as for monitoring inflammatory processes also in acute rheumatic and gashroin testinal diseases. To detect the presence of antibodies in blood that are sensitive to temperature changes cold agglutinins test is performed, finally serum sample was tested for cryoprecipitation to detect immune complex. Different types of joints and their classification is included in this present study. And types of movements at synovial joints, classification of Arthritis like osteoarthritis, rheumatoid arthritis, neuropathic arthropathy, metabolic arthritis etc where studied, out of twenty arthritis patients rheumatoid factor was detected in ten samples, c-reactive protein detected in nine samples, cold agglutination detected in one sample, and immuno compleres were detected in two samples of sera both rheumatoid factor and c-reactive proteins were detected. In two RF, CRPS, Ic. In 4at synorial fluid Rheumatoid factor and c-reactive proteins were detected. Our study includes that most of arthritis observed in females and mainly Rheumatoid arthritis. Serologically c-reactive protein detected in most of the patients.